Phenacetin Powder US Domestic Shipping whatsapp+8613302415760
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1. Quick Detail:
Phenacetin CAS: 62-44-2 EINECS Number: 200-533-0 Formula: C10H13NO2 MW: 179.2157 Density: 1.099g / cm3 Melting point: 133-138 ℃ Boiling point: 355.1 ° C at 760 mmHg Flash Point: 168.5 ° C Water-soluble: 0.076 g / 100 mL Vapor Pressure: 3.21E-05mmHg at 25 ° C Uses: Anti-inflammatory drugs Assay: 99% Appearance: White or almost white crystalline powder
2. Phenacetin Description:
Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug, which was widely used between its introduction in 1887 and the 1983 ban imposed by the FDA on its use in the United States. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized as paracetamol (acetaminophen), which replaced it in some over-the-counter medications following the ban on phenacetin.
3. Phenacetin Usage:
It is also called acetophenetidin. Having glossy leaflets or scales-like crystals that have no odor or taste.
Melting point 134 ~ 137. Stable in air, soluble in water, slightly soluble in boiling water, slightly soluble in ether, soluble in ethanol, chloroform. It is formed through the etherification,reduction and Acetylation reaction of p-chloronitrobenzene. As chloroacetanilide antipyretic and analgesic agent. Suitable for fever,headache, neuralgia and other drugs as a compound agent.
Antipyretic effect is stronger than the analgesic effect. Effect of strength is slow and long-lasting as aspirin, low toxicity. Research shows that: This product and its metabolites acetaminophen have the antipyretic effect. Because the enzyme inhibitor make phenacetin not be converted into paracetamol, still showed obvious antipyretic effect,thus the antipyretic effect after the product line not converrt to paracetamol.The mild phenacetin analgesic effect usually lasts 3 to 4 hours; and synergistic effect, of alicylic acid coadministrationmake the analgesic effect enhancement. The main clinical is for small animal antipyretic analgesic. This product is also a component of the APC tablet.
