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Azaperone Basic Info
Product Name: Azaperone Synonyms: AZAPERON;AZAPERONE; CAS: 1649-18-9 MF: C19H22FN3O MW: 327.4 EINECS: 216-715-8 Chemical Properties Off-White Solid Product Categories: Active Pharmaceutical Ingredients;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;ASTENIL;Inhibitors Melting point 87-89℃ Storage temp. 0-6°C Chemical Properties Off-White Solid Usage H1 antihistamine (nonsedating); leucotriene synthesis blocker Usage Sedative; tranquilizer. purity: 99%
Azaperone Description
Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. It is uncommonly used in humans as an antipsychotic drug .
Azaperone Application
Azaperone acts primarily as a dopamine antagonist but also has some antihistaminic and anticholinergic properties as seen with similar drugs such as haloperidol. Azaperone may cause hypotension and while it has minimal effects on respiration in pigs, high doses in humans can cause respiratory depression .
The most common use for azaperone is in relatively small doses to reduce aggression in farmed pigs, either to stop them fighting or to encourage sows to accept piglets. Higher doses are used for anesthesia in combination with other drugs such as xylazine, tiletamine and zolazepam. Azaperone is also used in combination with strong narcotics such as etorphine or carfentanil for tranquilizing large animals such as elephants. Use in horses is avoided as adverse reactions may occur.
