Skin Care Pharmaceutical Raw Materials Tranexamic Acid
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Tranexamic acid Product Name:Tranexamic acid
Tranexamic acid Synonyms:4-(Aminomethyl)cyclohexanecarboxylic Acid (cis- and trans- mixture);4-(Aminomethyl)cyclohexanecarboxylic acid;Tranexamic acid Tranexamic acid CAS:1197-18-8 MF:C8H15NO2 MW:157.21 Tranexamic acid EINECS:214-818-2 Tranexamic acid Product Categories:4-Substituted Cyclohexanecarboxylic Acids;Amines;Chiral Reagents;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds Tranexamic acid mp:233 °C Chemical Properties:White Solid Tranexamic acid Usage:Labelled Tranexamic Acid,Tranexamic acid (T714505) impurity.
Tranexamic Acid Descrption
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue.
Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. Tranexamic acid comes in oral and intravenous forms.
Side effects are uncommon and include gastrointestinal effects, dizziness, fatigue,
headache, and hypersensitivity reactions.Tranexamic acid needs to be used cautiously in people with kidney disease and who are at a high risk for blood clots.Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women.Tranexamic acid is an antifibrinolytic.
Tranexamic Acid Application
Tranexamic acid (TXA) is used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding.It comes in oral and intravenous forms.
Tranexamic acid is frequently used following major trauma.Tranexamic acid is used to prevent and treat blood loss in a variety of situations, such as dental procedures for hemophiliacs, heavy menstrual bleeding, and surgeries with high risk of blood loss.
Trauma:Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma.However, its benefit only appears to be within the first three hours.
Heavy menstrual bleeding:Tranexamic acid is used treat heavy menstrual bleeding.When taken by mouth it is both safely and effectively treated regularly occurring heavy menstrual bleeding.Another study demonstrated that the dose does not need to be adjusted in people who are between ages 12 and 16.
Surgery:Tranexamic acid is used in orthopedic surgery to reduce blood loss, to the extent of reducing or altogether abolishing the need for perioperative blood collection. It is of proven value in clearing the field of surgery and reducing blood loss when given before or after surgery. Drain and number of transfusions are reduced. However, the hidden blood loss is not reduced. Still, it is becoming an important tool in the anaesthetist's arsenal. It is commonly used in joint replacement surgery.
Use of tranexamic acid in surgical corrections of craniosynostosis in children reduces the need for blood transfusions.