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Local Anesthetic Drugs Numbing Skin Tissue Lidocaine

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Name: Lidocaine CAS No.: 137-58-6 Molecular Structure of 137-58-6 (Lidocaine) Formula: C14H22N2O Molecular Weight: 234.34 EINECS: 205-302-8 Density: 1.026 g/cm3 Melting Point: 66-69 °C Boiling Point: 350.8 °C at 760 mmHg Flash Point: 166 °C

Lidocaine, also known as xylocaine and lignocaine, is a medication used to numb tissue in a specific area and to treat ventricular tachycardia. It can also be used for nerve blocks. Lidocaine mixed with a small amount of epinephrine is available to allow larger doses to be used as numbing and to make it last longer. When used as an injectable it typically begins working within four minutes and lasts for half an hour to three hours. Lidocaine may also be applied directly to the skin for numbing

What is the Lidocaine base ?

Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration

of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action.

It can stop Epinephrine vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia.

Application :

Topical lidocaine has been shown in some patients to relieve the pain of postherpetic neuralgia (a complication of shingles), though there is not enough study evidence to recommend it as a first-line treatment. IV lidocaine also has uses as a temporary fix for tinnitus. Although not completely curing the disorder, it has been shown to reduce the effects by around two thirds.

Lidocaine hydrochloride injection administered intravenously or intramuscularly, is specifically indicated in the acute management of ventricular arrhythmias such as those occurring in relation to acute myocardial infarction, or during cardiac manipulation, such as cardiac surgery..

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