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Tetracaine Quick detail :
Product Name Tetracaine Synonym Anetain, Amethocaine, Pontocaine,Ametop,Dicaine CAS 94-24-6 MF C15H24N2O2 MW 264.36 EINECS 202-316-6 Assay 99% Quality Standards Enterprise Standard/Pharma Grade Appearance White powder Package 25kg/Drum
what is the Tetracaine ?
Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Application
(1) In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.
(2) Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
(3) Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
Tetracaine Dosage:
Tetracaine is given as an injection through a needle placed into an area of your middle or lower back near your spine. You will receive this injection in a hospital setting.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving tetracaine injection.
Spinal numbing medicines can have long-lasting effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about these effects.
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
Since tetracaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.
