Local Anesthetic Powder Prilocaine for Anti-Paining
we factory direct serve steroid powder, steroid oil sarms raw powder and peptides with top quality and best offer. We have professional disgusied packages, desigend according to different countries and different quantities, guarantee the safe delivery. We encourage start from small little quantity to test our quantity and service first.
Wikr:puresteroid
Skype: +8613302415760
Whatsapp: +8613302415760
Email: cindy1114@yccreate.com
Quick Details:
Product Name: Prilocaine (Base) Synonyms: 2-(propylamino)-o-propionotoluidid;2-(Propylamino)-o-propionotoluidide;2-Methyl-alpha-propylaminopropionanilide;alpha-n-Propyl-amino-2-methylpropionanilide;alpha-n-propylamino-2-methylpropionanilide;Astra 1512;Astra 1515;astra1512 CAS: 721-50-6 MF: C13H20N2O MW: 220.31 EINECS: 211-957-0 Categories: Active Pharmaceutical Ingredients Description: White or almost white powder Solubility: Very soluble in alcohol and in acetone; slightly soluble in water. Melting point: 36℃～39℃ Assay: 99.67% Standard: USP37 Mini order: 100g Main Functions:Local anesthetic. Shelf Life: 36 months Storage: Store in sealed containers at cool & dry place. Keep away from light, moisture, pest infestation.
Prilocaine------Description
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form (trade name Citanest), it is often used in dentistry.
Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia.
Prilocaine------Applications
Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
Prilocaine Usage And Synthesis:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
Pharmacological:
Its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6 ~ 7min and the duration time of about 1.5 ~ 2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
Adverse reactions:
once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
Note:
patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
Prilocaine Usage and dosage:
infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours. Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours. Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
