Prohormones Steroids Raw Powder Estriol for Health Care
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Estriol Synonyms: oestriol; 1,3,5(10)-Estratriene-3,16a,17b-triol CAS: 50-27-1 Standards:USP30 Character: White crystalline powder. Product Categories:steriods Assay: 97.0%-102.0%, EINECS: 200-022-2 MF:C18H24O3 MW:288.38 Packing: foil bag or tin. Delivery: Express courier. Usage: A metabolite of Estradiol. An estrogenic metabolite considerably less potent than the hormone Estradiol. pharmaceutical material, Steroid hormone, estrogen.
Description of Estriol :
Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy.
Though initial research in the 1970s suggested it could be used therapeutically as an estrogen,subsequent research failed to confirm this hypothesis. In pregnant women with multiple sclerosis, estriol reduces the disease's symptoms noticeably, according to researchers at UCLA's Geffen Medical School.
Estriol can be a weak or strong estrogen depending on if it is given acutely or chronically when given to immature animals, but is an antagonist when given in combination with estradiol.
Estriol may play a role in the development of breast cancer, but based on in vitro research, does appear to act as an antagonist to the G-protein coupled estrogen receptor. Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.
Applications:
Estriol's strength is actually found in its weakness. Tests show that while relieving the symptoms of perimenopause and menopause, estriol doesn't seem to increase the risk of breast cancer. This is because estriol binds to the estrogen receptors on the breast cells, but it has much weaker activity. Therefore, it actually blocks the stronger estradiol from binding to those cells and subjecting them to the higher estrogenic activity which has been shown to be protective against breast cancer. And for women who have difficulty tolerating stronger estrogens for the treatment of hormonal imbalance due to aging, estriol is often the right choice. For women experiencing symptoms of perimenopause or menopause, your BodyLogicMD affiliated doctor may test your estriol levels.
